The significant increase in the incidence of antibiotic resistance in bacteria observed in recent years represents a significant challenge to public health microbiology worldwide. Not least among these challenges are extended-spectrum β-lactamases (ESBLs) and carbapenemases among Enterobacteriaceae and other Gram-negative micro-organisms and vancomycin resistance among enterococci.
The UK Health Security Agency's Antimicrobial Resistance and Healthcare Associated Infections Reference Unit (AMRHAI) is the national reference laboratory responsible for the detection and investigation of antibiotic resistance, especially in healthcare associated bacterial pathogens, and offers molecular detection of the genetic determinants of certain key resistances.
NCTC, working in partnership with AMRHAI, offers a range of reference strains with characterised resistance mechanisms as well as susceptibility controls strains recommended by the European Committee on Antimicrobial Susceptibility Testing (EUCAST), the Clinical and Laboratory Standards Institute (CLSI) and Public Health England.
Download the NCTC Antimicrobial Resistant Strains brochure
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