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UK Health Security Agency

Klebsiella pneumoniae

Klebsiella pneumoniae

Catalogue No.

NCTC 14052

Current Name

Klebsiella pneumoniae

Type Strain

Reference Strain

Original Strain Reference

SGH10

Culture Conditions

Growth Conditions on Solid Media

Nutrient agar, 24 hours, 37°C, O₂

Biological and Genomic Info

Antigenic Properties

Klebsiella capsular serotype K1

Antimicrobial Susceptibility

Ampicillin resistant.

Whole Genome Sequence

NCBI: CP025080, CP025081

Other Typing Conditions

MLST 23, Clonal Group 23, Clonal Group 23 Sublineage I

Gram Stain Result

Positive

Additional Info

Accession Date

23/11/2017

Depositor

Prof. Gan Yunn-Hwen (Dept. of Biochemistry, National University of Singapore, Singapore)

Isolated From

Human patient. Klebsiella-induced liver abscess, Singapore General Hospital, 01/03/2015.

History

Accessioned into NCTC < Prof Gan Yunn-Hwen < Dr Jeanette Teo (Dept. of Laboratory Medicine, National University Hospital, Singapore) < Isolated by Associate Prof. Tse Hsien Koh (Singapore General Hosptial, Singapore)

Applications

Applications

Use in experimental models of pathogenicity of hypervirulent K. pneumoniae. Representitive of the globally disseminated sequence type 23 clonal group 23 lineage of K. pneumoniae which is associated with hypervirulence and liver abscesses.

Bibliography

Lee IR et al. Differential host susceptibility and bacterial virulence factors driving Klebsiella liver abscess in an ethnically diverse population. Sci Rep. 6:29316. MMC Lam, KL Wyres et al. Population genomics of hypervirulent Klebsiella pneumoniae clonal-group 23 reveals early emergence and rapid global dissemination. Nat Commun. 2018, Jul 13;9(1):2703

Available Formats

  • Ampoule (Bacteria)

If use of this culture results in a scientific publication, it should be cited in the publication as: Klebsiella pneumoniae (NCTC 14052)

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