Oesophageal cell lines

We have a series of oesophageal adenocarcinoma (EAC) cell lines available. The majority of these cell lines have been studied by Boonstra et al., 2010, who in a world-wide effort sought to verify the authenticity of all available EAC cell lines by comparing the cell lines to the original primary tumour tissue from the donors.

Boonstra et al. discovered that cell lines SEG-1, BIC-1, and SK-GT-5 are not EAC cell lines but the following respectively: large cell lung cancer cell line H460, colorectal adenocarcinoma cell line SW620, and gastric fundus carcinoma cell line SK-GT-2. They also confirmed that cell lines FLO-1, KYAE-1, SK-GT-4, OE19, OE33, OACP4C, OACM5.1, ESO26, and ESO51 are derived from human EACs. All nine of these verified EAC cell lines, together with their genotyping information, have been deposited with ECACC.

Browse our oesophageal cell lines

Reference

Boonstra et al., (2010) Verification and Unmasking of Widely Used Human Esophageal Adenocarcinoma Cell Lines. J Natl Cancer Inst. Feb 24;102(4):271-4. PMCIM:PMC2902814.